Lignocaine crosses the placenta barrier and there are no adequate and well-controlled studies in pregnant women. Serious adverse effects of epidural anaesthesia are rare. Lignocaine blood levels after normal doses are low when used for surface anaesthesia. Hence, only little drug is available for placenta transfer. However, lignocaine may have transient effects on the neonatal auditory system. Lignocaine should be used in pregnancy only if clearly needed.
Lignocaine is distributed into breast milk. No adverse effect is seen in breastfed infants whose mothers were taking lignocaine.
Use at recommended doses is unlikely to affect the neonate.